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The role of synaptic transmission modulation in pain


Pain:

Pain is an unpleasant sensory and emotional experience associated with actual or potential tissue damage, or described by the terms of such damage.

 

Nociception:

The process of detecting and signalling the presence of a painful stimulus in the peripheral and central nervous system.

 

MEANING OF DORSAL HORN OF SPINAL CORD IN NOCICEPTIVE TRANSMISSION 

 

MEANING OF PAIN

 

ACUTE PAIN

Important signalling mechanism

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PATHOLOGICAL PAIN

Chronic (e.g. neuropathic) pain