Intranet Čeština

Neurophysiology of Memory

Neurophysiology of Memory Genetically modified rats lacking protein Nogo-A, which inhibits the growth of nerve fibers. The model has been crated in CIMH Mannheim and ETH Zurich. (photo: T. Petrasek)

Our department has been involved in learning, memory and cognitive functions studies for a long time. For instance, spatial orientation is now considered a type of so-called declarative memory (the ability to remember facts and events). This capability is dominantly affected in Alzheimer's disease and other dementias, obsessive-compulsive disorder or schizophrenia. These are conditions for which we do not know details of their physiology, so we actually treat only symptoms but not causes. Using neuroanatomical, neuropharmacological, cellular, molecular, and behavioural approaches we investigate brain function in relation to behavior, both in health and disease. In an intense collaboration, we also work on development of novel therapeutics focused on the brain diseases.

 

EXTERNAL WEBSITE OF THE DEPARTMENT

Projects

Achievements

Frontiers in Behavioral Neuroscience, 2015

Svoboda J, Stankova A, Entlerova M, Stuchlik A. Acute administration of MK-801 in an animal model of psychosis in rats interferes with cognitively demanding forms of behavioral flexibility on a rotating arena. Front Behav Neurosci. 2015; 9:75. IF = 3.3 (2014). More

Article Frontiers in Behavioral Neuroscience 9, 2015

Mabel Rodriguez, Filip Spaniel, Lucie Konradova, Katerina Sedlakova, Karolina Dvorska, Jitka Prajsova, Zuzana Kratochvilova, David Levcik, Kamil Vlcek, and Iveta Fajnerova. Comparison of visuospatial and verbal abilities in first psychotic episode of schizophrenia spectrum disorder: impact on global functioning and quality of life. Frontiers in Behavioral Neuroscience 9, 2015. More

Publications

Svoboda, Jan - Popelíková, Anna - Stuchlík, Aleš . Drugs interfering with Muscarinic Acetylcholine Receptors and Their effects on Place Navigation . Frontiers in Psychiatry. 2017, roč. 8, Nov 9, článku 215 . IF = 3.532 [ASEP] [ doi ]
Svoboda, Jan - Lobellová, Veronika - Popelíková, Anna - Ahuja, Nikhil - Kelemen, Eduard - Stuchlík, Aleš . Transient inactivation of the anterior cingulate cortex in rats disrupts avoidance of a dynamic object . Neurobiology of Learning and Memory.. 2017, roč. 139, Mar 2017, p. 144-148 . IF = 3.543 [ASEP] [ doi ]
Pištíková, Adéla - Brožka, Hana - Stuchlík, Aleš . Adult Neurogenesis in the Hippocampus From a Perspective of Discrimination and Generalization: A Hypothesis . Physiological Research. 2017, roč. 66, 3, p. 441-448 . IF = 1.461 [ASEP]
Pištíková, Adéla - Brožka, Hana - Bencze, Michal - Radostová, Dominika - Valeš, Karel - Stuchlík, Aleš . The effect of hypertension on adult hippocampal neurogenesis in young adult spontaneously hypertensive rats and Dahl rats . Physiological Research. 2017, roč. 66, 5, p. 881-887 . IF = 1.461 [ASEP]
Laczó, J. - Marková, H. - Lobellová, Veronika - Gažová, I. - Pařízková, M. - Cerman, J. - Nekovářová, Tereza - Valeš, Karel - Klovrzová, S. - Harrison, J. - Windisch, M. - Vlček, Kamil - Svoboda, Jan - Hort, J. - Stuchlík, Aleš . Scopolamine disrupts place navigation in rats and humans: a translational validation of the Hidden Goal Task in the Morris water maze and a real maze for humans . Psychopharmacology. 2017, roč. 234, 4, p. 535-547 . IF = 3.308 [ASEP] [ doi ]

Article photogallery

The entire photogallery

Contacts

Institute of Physiology AS CR, v.v.i.
Department of Neurophysiology of Memory

Vídeňská 1083
14220 Prague 4
Czech Republic
tel. +420 241 062 577
   
   

ales.stuchlik@fgu.cas.cz

People

 

prof. RNDr. Aleš Stuchlík, DSc.
head of the department

 
 

RNDr. Jan Svoboda, Ph.D.

deputy head of the department

 
 

RNDr. Štěpán Kubík, Ph.D. 

senior researcher

 
 

Mgr. Kamil Vlček, Ph.D.

senior researcher

 
 

MUDr. Daniel Klement, Ph.D.

senior researcher

Mgr. David Levčík, Ph.D.
postdoc

 
 

EXTERNAL

 
 

RNDr. PhDr. Tereza Nekovářová, Ph.D.

senior researcher

 
 

RNDr. Karel Valeš, Ph.D.
senior researcher

 
 

Mgr. Iveta Fajnerová, Ph.D.
postdoc

 
  Mgr. Tomáš Petrásek, Ph.D.
postdoc
 
 

DOCTORANDS

 
  Mgr. Kristína Holubová
PhD student
 
  Mgr. Eliška Antošová
PhD student
 
  Mgr. Hana Hatalová-Brožka
PhD student
 
  Mgr. Markéta Chvojková
PhD student
 
  Mgr. Lenka Kletečková
PhD student
 
 

Mgr. Kristýna Malenínská

PhD student

 
  Mgr. Iveta Vojtěchová
PhD student
 
  Mgr. Helena Buchtová 
PhD student
 
  Mgr. Adéla Pištíková
PhD student
 
 

Mgr. Martina Janíková

PhD student

 
 

TECHNICIANS

 
 

Veronika Lobellová

technician

 
  Michaela Fialová
technician
 
  Jindřich Kalvoda
IT specialist
 
  Jana Machková
technician
 
  Barbara Stuchlíková
technician
 
  Antonín Zahálka
technician
 
  Vladimíra Marková
personal assistant
 
  Lenka Rosenkrancová, Dis.
personal assistant (maternity leave)
 

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