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Biological Rhythms - annotation


The PhD project aims to determine the basic mechanisms of circadian clock development in the fetal brain and its sensitivity to maternal stress. Studies will use animal models, including transgenic mice with circadian reporter. A wide range of behavioral and molecular techniques used in the field of circadian clocks, including transcriptome/proteome/metabolome analyzes, real-time recording of clock gene expression in organotypic explants of brain areas, and AAV transfection, will be employed.