Metabolomics 2.0: Comprehensive analytical methods and bioinformatics tools for the study of circadian rhythms

• PI: T. Cajka, Laboratory of Translational Metabolism
• Project code: LTAUSA19124
• Period: 2020–2022
• Funding: Ministry of Education, Youth and Sport of the Czech Republic

Annotation

The aim of this project is to establish cooperation and active scientific activity between the Laboratory of Translational Metabolism, Laboratory of Metabolomics and Laboratory of Biological Rhythms (Institute of Physiology of the Czech Academy of Sciences) and the West Coast Metabolomics Center (University of California, Davis). The project focuses on the development of complex analytical methods and bioinformatics tools for the study of circadian rhythms. Recent improvements in chromatography and mass spectrometry methods, together with huge advances in computational approaches, means the time is right to develop second-generation metabolomics tools (Metabolomics 2.0) for the study of circadian rhythms. Scientific publications with detailed information needed for effective transfer of the methods will be available for other research institutions focusing on similar topics.