Intranet Campus web

INSTITUTE OF PHYSIOLOGY CAS

Cutting-edge science for health

Cognitive deficit - symptom of many of neuropsychiatric disorders

Original sample of 12 publications including also report from collection of virtual-reality data from schizophrenia patients and healthy volunteers published in the special issue of Frontiers in Behavioral Neuroscience.

Cognitive deficit (i.e., disturbance of mental function) can be observed in many neuropsychiatric disorders, in some cases, cognitive deficit is primary and a very stable symptom. Typical diseases affecting the function are Alzheimer´s disease, schizophrenia etc.

Original sample of 12 publications from our department was published in special issue of Frontiers in Behavioral Neuroscience, focused on cognitive impairments in neuropsychiatric disorders. The sample involved extremely interesting paper such as report from collection of virtual-reality data from schizophrenia patients and healthy volunteers. requested the “solve the navigation maze“ with a joystick. Moreover, there are many others intriguing and controversial studies, including transgenic animals.

 

 


Nekovářová, Tereza - Yamamotová, A. - Valeš, Karel - Stuchlík, Aleš - Fricová, J. - Rokyta, R.
Common mechanisms of pain and depression: are antidepressants also analgesics? 
Frontiers in Behavioral Neuroscience. Issue 8, Mar 25 (2014), p. 99. ISSN 1662-5153
IF: 4.758

Fajnerová, Iveta - Rodriguez, M. - Levčík, David - Konrádová, L. - Mikoláš, P. - Brom, C. - Stuchlík, Aleš - Vlček, Kamil - Horáček, J.
A virtual reality task based on animal research – spatial learning and memory in patients after the first episode of schizophrenia. 
Frontiers in Behavioral Neuroscience. Issue 8, May 27 (2014), p. 157. ISSN 1662-5153
IF: 4.758

Hatalová, Hana - Radostová, Dominika - Pištíková, Adéla - Valeš, Karel - Stuchlík, Aleš
Spatial reversal learning in chronically sensitized rats and in undrugged sensitized rats with dopamine D2-like receptor agonist quinpirole. 
Frontiers in Behavioral Neuroscience. Issue 8, APR 11 (2014), p. 122. ISSN 1662-5153
Grant CEP: GA MZd(CZ) NT13386
IF: 4.758

Holubová, Kristina - Nekovářová, Tereza - Pistovčáková, J. - Šulcová, A. - Stuchlík, Aleš - Valeš, Karel
Pregnanolone glutamate, a novel use-dependent NMDA receptor inhibitor, exerts antidepressant-like properties in animal models. 
Frontiers in Behavioral Neuroscience. Issue 8, Apr 16 (2014), p. 130. ISSN 1662-5153
IF: 4.758

Nekovářová, Tereza - Fajnerová, Iveta - Horáček, J. - Španiel, F.
Bridging disparate symptoms of schizophrenia: a triple network dysfunction theory. 
Frontiers in Behavioral Neuroscience. Issue 8, May 30 (2014), p. 171. ISSN 1662-5153
IF: 4.758

Rambousek, Lukáš - Páleníček, T. - Valeš, Karel - Stuchlík, Aleš
The effect of psilocin on memory acquisition, retrieval, and consolidation in the rat. 
Frontiers in Behavioral Neuroscience. Issue 8, May 16 (2014), p. 180. ISSN 1662-5153
IF: 4.758

Stuchlík, Aleš
Dynamic learning and memory, synaptic plasticity and neurogenesis: an update. 
Frontiers in Behavioral Neuroscience. Issue 8, APR 1 (2014), p. 106. ISSN 1662-5153
IF: 4.758

Vlček, Kamil - Laczó, J.
Neural correlates of spatial navigation changes in mild cognitive impairment and Alzheimer's disease. 
Frontiers in Behavioral Neuroscience. Issue 8, Mar 17 (2014), p. 89. ISSN 1662-5153
IF: 4.758

 

More about the research projects of Department of Neurophysiology of Memory can be found on its web site.