Cutting-edge science for health


Memory Park´s psychological tests attracted over 1200 people (24.3. 2021)

Vybrané psychologické testy, které FGÚ zpřístupnilo, jako součást letošního online Týdne mozku měly úspěch. Během týdenní akce si jeden z testů zkusilo udělat 1261 lidí, alespoň jeden test dokončilo 1023 lidí a alespoň jeden dotazník vyplnilo 864 lidí (úplná statistika testů). Zájemci si mohli vyzkoušet test pracovní a epizodické paměti, test převzetí perspektivy nebo test skrytého cíle. Testy jsou používané ke zjištění postižení paměti a prostorové orientace u pacientů s Alzheimerovou chorobou, epilepsií nebo schizofrenií. Testy je i nadále možné vyzkoušet na tomto odkazu.

Institute of Physiology registered the greatest interest of the applications for the internships. One-fifth of the all applications were sent there! 184 students, who sent in total 354 applications, were interested in internships at the Institute. Within the Open Science at the IPHYS, fiinally 8 internships for 16 selected students will be realized. Students were most interested in the topic "Epilepsy as a metabolic disease" supervised by Jakub Otáhal and also the topic supervised by Michaela Tencerová "How hard are the bones and what is hidden under them?". 31 institutes of the Czech Academy of Sciences participated in the whole project, 85 lecturers will lead 103 internships for 196 students. More about the Open Science project.

Tomáš Čajka is a co-author of the unique software for analyses of complex lipids in biological samples (15.1. 2021)

Processing of instrumental files acquired during untargeted metabolomics and lipidomics analyses represents a challenging task. It is estimated that only 20 percent of signals (features) collected during untargeted liquid chromatography–mass spectrometry (LC–MS) methods can be annotated. MS-DIAL represents user-friendly, open-access software for processing untargeted metabolomics and lipidomics instrumental files. The latest version contains an atlas (database) for 117 lipid subclasses with predicted retention times, tandem mass spectrometry spectra (MS/MS), and collision cross sections (CCS) for annotation of complex lipids in biological samples. Using MS-DIAL 4, a higher number of annotated complex lipids in biological samples is achieved compared to other software programs in this field permitting more meaningful data interpretation.

H. Tsugawa, K. Ikeda, M. Takahashi, A. Satoh, Y. Mori, H. Uchino, N. Okahashi, Y. Yamada, I. Tada, P. Bonini, Y. Higashi, Y. Okazaki, Z. Zhou, Z.-J. Zhu, J. Koelmel, T. Cajka, O. Fiehn, K. Saito, M. Arita, M. Arita: A lipidome atlas in MS-DIAL 4. Nature Biotechnology 38 (2020) 1159–1163. IF = 36.558 DOI

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